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Tumor-specific HPV-16 L1-specific CD8+ CTL responses induced by L1-pulsed DCs in Kcx19, Kcx21, and Kcx22 patients, measured in a 5-h 51Cr-release assay. Percentage lysis against autologous tumor cells and HLA-identical HPV-16-negative control LCL at different effector/target cell ratio is shown. Anti-HLA class I blocking antibody (W6/32) was used at 50 μg/ml. A representative experiment for each patient is shown.
