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. 2009 Apr 22;83(13):6477–6483. doi: 10.1128/JVI.00434-09

FIG. 5.

FIG. 5.

EV71-specific antibody reduces the lethality of infected mice by decreasing viral loads in tissues. The disease scores (A) and survival rates (B) of EV71-infected, B-cell-deficient mice given control antibody (n = 6) or EV71-specific antibody (n = 6) are shown. Disease scores that are significantly different (P < 0.001) by the Wilcoxon test are indicated (†††). Survival rates that are significantly different (P < 0.01) by the log-rank test are indicated (**). (C) The viral titers in the indicated tissues of infected, B-cell-deficient mice given control antibody (n = 6) or EV71-specific antibody (n = 6) 5 days after infection are shown. The data shown are the mean values plus SE values (error bars). Viral titers that are significantly different (P < 0.01) by the Mann-Whitney U test are indicated (§§).