TABLE 1.
Immunogenicities of the viral proteins testeda
Protein | No. of amino acids | Average total no. of spots per 106 cells | Normalized cytokine spot count | % Response relative to total no. of CD4 T cells |
---|---|---|---|---|
NA | 470 | 1,128 | 2.4 | 13.9 |
NP | 498 | 1,972 | 4.0 | 24.3 |
NS1 | 230 | 2,634 | 11.4 | 32.5 |
HA | 565 | 2,381 | 4.2 | 29.3 |
Total | 1,763 | 8,115 | 100 |
Shown are the numbers of amino acids in each of the viral proteins tested, the sums of the cytokine spot counts for all of the peptides in each protein (column 2), which were then divided by the numbers of amino acids in each protein to yield the normalized cytokine spot count. The normalized cytokine spot count for each protein is represented as a percentage of CD4 T cells dedicated to each protein relative to the total number of viral protein reactive cells.