Table 2.
Basal mRNA expression between young and old subjects
| Young | Old | P Value | |
|---|---|---|---|
| REDD1 | 1.13±0.30 | 2.18±0.72 | 0.21 |
| REDD2 | 1.07±0.14 | 0.88±0.18 | 0.43 |
| TSC1 | 1.02±0.09 | 1.04±0.09 | 0.88 |
| TSC2 | 1.02±0.09 | 1.26±0.08 | 0.09† |
| Rheb | 1.01±0.05 | 0.93±0.03 | 0.25 |
| TCTP | 1.09±0.20 | 1.34±0.26 | 0.45 |
| cMyc | 1.13±0.23 | 2.12±0.53 | 0.12 |
| PRAS40 | 1.10±0.19 | 1.38±0.34 | 0.50 |
| hVps34 | 1.05±0.13 | 2.45±0.50 | 0.02* |
| MAP4K3 | 1.08±0.19 | 1.49±0.19 | 0.15 |
| mTOR | 1.05±0.14 | 1.18±0.23 | 0.64 |
| S6K1 | 1.02±0.09 | 1.31±0.21 | 0.24 |
| mib2 | 1.09±0.21 | 1.37±0.37 | 0.52 |
| myostatin | 1.17±0.27 | 1.08±0.34 | 0.84 |
| IGF-1R | 1.08±0.18 | 1.41±0.23 | 0.29 |
| myoD | 1.06±0.16 | 1.59±0.19 | 0.06† |
| myogenin | 1.09±0.21 | 2.04±0.42 | 0.07† |
Data expressed as fold change from young (mean ± SE).
*
Significantly different from young P < 0.05.
†
Significantly different from young P ≤ 0.09.
Values determined by the 2−ΔΔCt method.