Fig. 1.
Outline of the protocol for part 1. Four skin sites on the ventral aspect of the forearm were randomly chosen. Two were pretreated with ice for 5 min; one of these was sites was instrumented with a microdialysis probe. A skin site not treated with ice was also instrument with a microdialysis probe. This arrangement yielded untreated control, ice pretreatment only, microdialysis fiber only, and both ice and microdialysis fiber. Ninety minutes were allowed to elapse before data collection. Baseline measurements were then recorded for 10 min, and whole body heat stress was performed for 30–45 min, until oral temperature was raised by 0.7°C. LW, local warming; Tskin, whole body mean skin temperature; Tloc, local skin temperature; Temp, temperature; N/A, not applicable.