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Cartoon depicting a possible function of Hg2+-sensitive Lck Y192 (transitory) phosphorylation in the initiation of TCR signal transduction. A) Presignal. B) Signal initiation. C) Time point ∼15 s. D) Time point ∼30 s. E) Time point ∼60 s. F) Signal initiation attenuated in the presence of Hg2+.
