Figure 2.

Time-dependent increase in core temperature during heat challenge is greater in CASQ1-null mice. A) Increase in internal temperature during heat stress (41°C, 30 min) in CASQ1-null and WT male and female mice. B) Semilog plot showing results of Student’s t test performed during 30 min of exposure to heat (calculated every 2 min). C) Table summarizing absolute and relative changes in internal core temperatures in male and female WT and CASQ1-null mice at beginning (t₀) and end (t₃₀) of heat stress protocol.