TABLE 1.
Parameter | ATX (n=6)
|
Vehicle (n=6)
|
||
---|---|---|---|---|
Before | After | Before | After | |
pH | 7.37 ± 0.01 | 7.44 ± 0.02 | 7.40 ± 0.02 | 7.41 ± 0.02 |
PaCO2 (mmHg) | 42.00 ± 1.79 | 40.67 ± 2.14 | 39.67 ± 1.23 | 41.83 ± 2.12 |
PaO2 (mmHg) | 92.50 ± 4.02 | 83.83 ± 1.76 | 87.83 ± 2.55 | 87.17 ± 2.44 |
BP (mmHg) | 99.67 ± 8.82 | 105.33 ± 10.93 | 97.00 ± 8.27 | 100.67 ± 8.19 |
Brain temp. (°C) | 35.77 ± 0.56 | 36.3 ± 0.17 | ||
Body temp. (°C) | 36.07 ± 0.22 | 36.38 ± 0.14 |
Data recorded before and 20-30 min after i.c.v. administration of ATX. Values are presented as means ± se. BP, blood pressure; temp., temperature.