Fig. 1.
CML immunostaining of protein from different regions of the brain in young and aged mice. (A) Representative immunoblots from homogenates of each brain region for two young (upper) and two old (lower) mice. Average whole lane intensity of CML immunoblots normalized with alpha-tubulin (B) and average number of visible CML-stained bands (C) are shown for the six brain regions. Each value represents the mean ± SE of 11 young or 24 old mice.
* indicates a significant difference between young and old groups (p<0.05).
Abbreviation: CX, cerebral cortex; CB, cerebellum; MB, midbrain; BRS, brainstem; ST, striatum; HP, hippocampus