Table 3.
Pearson correlation coefficients denoting association between CML immunostaining in different brain regions of old mice and measures of learning/memory
| Brain Region |
|||||||
|---|---|---|---|---|---|---|---|
| Learning/Memory | CX | CB | MB | BRS | HP | ST | WhBr |
| Swim Maze | |||||||
| Total learning index (cm) | −0.267 | −0.177 | 0.059 | 0.093 | 0.123 | −0.064 | −0.069 |
| Acquisition learning index (cm) | −0.092 | −0.121 | −0.147 | −0.026 | 0.206 | 0.060 | −0.061 |
| Reversal learning index (cm) | −0.321 | −0.163 | 0.207 | 0.159 | 0.014 | −0.145 | −0.052 |
| Maximum spatial learning (cm) | −0.220 | 0.094 | −0.184 | −0.233 | 0.411 | −0.054 | −0.251 |
| Target Quadrant (% time spent) | 0.167 | −0.111 | −0.227 | 0.391 | −0.270 | 0.210 | 0.321 |
| Annulus 40 (% time spent) | −0.156 | 0.056 | −0.268 | 0.152 | −0.065 | −0.063 | 0.015 |
| Annulus 20 (% time spent) | −0.053 | −0.026 | −0.402 | 0.070 | −0.010 | −0.103 | 0.009 |
| Platform entries (counts) | −0.176 | 0.070 | −0.178 | 0.102 | −0.077 | −0.125 | −0.025 |
| Avoidance learning | |||||||
| Session 1 (number of trials) | −0.077 | 0.053 | −0.013 | −0.033 | 0.120 | 0.259 | −0.050 |
| Session 2 (number of trials) | 0.009 | −0.130 | 0.303 | 0.246 | −0.324 | −0.341 | 0.154 |
Abbreviations: CX, cerebral cortex; CB, cerebellum; MB, midbrain; BRS, brainstem; HP, hippocampus; ST, striatum; WhBr, whole brain