Table 2. Association of GST Polymorphisms and SPM Risk.

Genotypes	Total		SPM-Free		SPM			Adjusted HR1
	No.	%	No.	%	No.	%	P-value*	(95% CI)
GSTM1							0.221
Wild-type	601	49.6	553	50.2	48	44.0		1.0
Null	610	50.4	549	49.8	61	56.0		1.4 (0.9-2.0)
GSTT1
Wild-type	960	79.3	875	79.4	85	78.0	0.727	1.0
Null	251	20.7	227	20.6	24	22.0		1.1 (0.7-1.8)
GSTM1 + GSTT1							0.494
M1 Wild and T1 Wild	470	38.8	433	39.3	37	33.9		1.0
Either M1 Null or T1 Null	621	51.3	562	51.0	59	54.2		1.3 (0.8-1.9)
M1 Null and T1 Null	120	9.9	107	9.70	13	11.9		1.6 (0.9-3.1)
Trend test								P = 0.116
GSTP1_105							0.028
Ile/Ile	484	40.1	451	41.1	33	30.3		1.0
Ile/Val + Val/Val	723	59.9	647	58.9	76	69.7		1.7 (1.1-2.5)
GSTP1_114							0.575
Ala/Ala	1021	84.4	927	84.2	94	86.2		1.0
Ala/Val + Val/Val	189	15.6	174	15.8	15	13.8		0.8 (0.5-1.5)
No. of GSTP1 risk genotypes							0.086
0	462	38.3	431	39.2	31	28.7		1.0
1-2	678	56.2	609	55.5	69	63.9		1.6 (1.1-2.5)
3-4	66	5.50	58	5.30	8	7.40		2.0 (0.9-4.3)
Trend test								P = 0.018

^*P values were calculated from chi-square test

¹Adjusted for age, sex, ethnicity, smoking, and alcohol