Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
miR-22 represses estrogen signaling by ERα. Constructs expressing wild-type and mutant versions of miR-22 were cotransfected with the ERα reporter into MCF7-SH cells to assay endogenous ERα activity. The results obtained with an shRNA control were arbitrarily set to 100%.
