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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Surg Res. 2008 Jun 23;154(1):135–142. doi: 10.1016/j.jss.2008.05.025

Figure 1.

Figure 1

Figure 1

Figure 1

Figure 1

(A) Changes in the ratio of intimal to medial areas and the intimal area of cells, collagen, proteoglycan and elastin in wire injured femoral vessels over time from day 0 to day 56. (B) A comparison of the effect of pluronic gel with and without GM6001 (general MMP inhibitor) and aprotinin (plasminogen activation inhibitor) on intimal hyperplasia development at 28 days after wire injury. (C) Changes in the area of cells, collagen, proteoglycan and elastin in wire injured femoral vessels in the presence of pluronic gel with and without GM6001 and aprotinin at 28 days after wire injury. (D) Changes in cell proliferation, cell apoptosis and cell migration in wire injured femoral vessels in the presence of pluronic gel with and without GM6001 and aprotinin. Values are the mean± s.e.m. (n=6 per group or time point). Statistical differences between groups were tested with a Kruskal-Wallis non-parametric test with post hoc Dunn’s multiple comparison correction, where appropriate.