Skip to main content

View full-text article in PMC

. 2009 Jun 7;10:52. doi: 10.1186/1471-2350-10-52

Table 4.

Risk of acute coronary syndrome in relation to use of NSAID. Aspirin users are included in 'No NSAID'

PPARγ Pro¹²Ala	N_cases/N_non-cases		HR^a95% CI				HR^b95% CI
Men	NSAID		NSAID				NSAID
	NO	YES	NO		YES		NO		YES
Pro/Pro	531/622	58/42	1.00	-	1.63	1.07–2.47	1.00	-	1.58	1.00–2.48
Pro/Ala	156/190	20/14	0.91	0.75–1.17	1.61	0.79–3.25	0.91	0.70–1.17	1.63	0.79–3.37
Ala/Ala	20/11	1/1	2.07	0.99–4.32	2.00	0.13–30.5	2.36	1.09–5.13	1.10	0.07–17.7
P for interaction						0.918				0.670

Pro/Pro	531/622	58/42	1.00	-	1.63	1.07–2.47	1.00	-	1.58	1.00–2.48
Pro/Ala & Ala/Ala	176/201	21/15	0.96	0.77–1.24	1.62	0.72–3.23	0.97	0.76–1.25	1.60	0.79–3.23
P for interaction						0.958				0.929
Women
Pro/Pro	145/505	36/76	1.00	-	1.52	0.96–2.41	1.00	-	1.37	0.84–2.23
Pro/Ala	52/168	10/25	0.99	0.67–1.45	1.31	0.59–2.87	0.93	0.62–1.38	1.33	0.59–3.00
Ala/Ala	2/9	0/6	0.61	0.12–2.97	-	-	0.54	0.11–2.71	-	-
P for interaction						0.771				0.924

Pro/Pro	145/505	36/76	1.00	-	1.42	0.96–2.41	1.00	-	1.36	0.84–2.23
Pro/Ala & Ala/Ala	54/177	10/31	0.96	0.66–1.41	1.08	0.50–2.32	0.90	0.61–1.34	1.14	0.52–2.51
P for interaction						0.517				0.875

a) crude

b) adjusted for smoking status and alcohol consumption