Table 1.
Mortality rates in cases of upper gastrointestinal bleed or perforation according to date of publication and size of study, for all cases and those taking NSAID
| All Cases | Cases using NSAIDs | |||||
|---|---|---|---|---|---|---|
| Number of | Number of | |||||
| Analysis | Cases | Deaths | Mortality (%; 95% CI) | Cases | Deaths | Mortality (%; 95% CI) |
| Overall | 61067 | 5001 | 8.2 (8.0 to 8.4) |
5526 | 904 | 16.4 (15.4 to 17.3) |
| By date of publication | ||||||
| Before 1997 [1] | 11361 | 1319 | 11.6 (11.0 to 12.2) |
4046 | 595 | 14.7 (13.6 to 15.8) |
| Between 1997 and 2008 | 49706 | 3682 | 7.4 (7.2 to 7.6) |
1480 | 309 | 20.9 (18.8 to 22.9) |
| By number of cases | ||||||
| ≥ 2000 | 35058 | 2410 | 6.9 (6.6 to 7.1) |
3443 | 576 | 16.7 15.5 to 18.0) |
| 200–1999 | 23147 | 2345 | 10.1 (9.7 to 10.5) |
1465 | 297 | 20.3 (18.2 to 22.3) |
| 1–199 | 2862 | 246 | 8.6 (7.6 to 9.6) |
618 | 31 | 5.0 (3.3 to 6.7) |