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. 2009 Jun 18;106(27):11324–11329. doi: 10.1073/pnas.0901176106

Fig. 4.

Fig. 4.

Adrenalectomy prevents stress-induced increase in hypothalamic RFRP expression. (A) Stress led to a significant increase in plasma corticosterone in sham-operated solid line, (P = 0.001) but not ADX rats dashed line, (P = 0.891). (B) Two weeks of daily immobilization led to a significant increase in RFRP mRNA expression in the hypothalamus of sham operated (P = 0.050) but not ADX (P = 0.794) rats. Open bar = control; closed bar = stress. * P < 0.05 stress versus no stress or 0 hours versus 3 hours of stress as appropriate.