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. 2009 Jun 26;4(6):e6060. doi: 10.1371/journal.pone.0006060

Table 1. Background characteristics, incidence of symptomatic rotavirus infections per personyear of observation for children <2 years and bias assessment of 21 prospective studies included in the meta-analysis.

ref country (location) inc year of study (midpoint) study group/situation ses bias
[18] Canada (Winnipeg, Manitoba) 0.24 1977 mothers in early postpartum period recruited at Health Sciences Centre; not biased toward high socioeconomic class NL P
[41] Mexico (San Pedro Martir, around the southwestern outskirts of Mexico City) 0.38 1988 low income periurban area L N
[42], [67] Nigeria (Ibadan) 1 NR children born at a General Hospital; lower socioeconomic class L H
[43] Chile (Población Carlos Condell slum, City of Santiago) 0.19 1981 all families with children <7years age living in slum L P
[44] Mexico (rural village appr 180 km southwest of Mexico City) 0.33 1983 all children from the village U P
[45] Guinea-Bissau (suburban districts Bandim II and Bele of Bissau) 0.24 1997 houses were randomly selected PL N
[46] Central African Republic (Bangui) 0.14 1985 children in maternity ward (living in neighbourhood of the ward) PL H
[47] Argentina (Avellaneda District, a suburb of Buenos Aires) 0.13 1984 families recruited when seeing pediatrician at Primary Health Care Center; low socioeconomic level, shantytowns, unstable and overcrowded houses L H
[48] Guatemala (Cauqué) 0.84 1967 Mayan Indians; crowded L N
[49] Bangladesh (Mirpur, Dhaka) 0.25 2003 urban slum L P
[50] US (Northern Virginia) 0.22 1978 patients from a group pediatric practice; middle-class suburban population NL H
[51] Palestina (Gaza: Jebaliya) 0.08 1985 crowded, poor L P
[52] Costa Rica (Puriscal) 0.06 1983 children born in Hospital San Juan de Dios in San José (97% of babies from Puriscal are born here) NL N
[53] China (suburb of Hong Kong) 0.06 NR low- to low-middle income families U H
[54] Nicaragua (Léon) 0.23 1992 children born in university hospital of whom mothers lived in one of the 3 health areas in the city NL N
[55] Bangladesh (10 villages in Mirzapur, rural area appr 60 km from Dhaka) 0.21 1994 door-to-door census; crowded, poor L N
[56] Egypt (2 villages in the vicinity of a rural district appr 40 km from Alexandria) 0.29 1995 house-to-house census U N
[57] Bangladesh (Enayet Nagar and Sepai Kandi) 0.41 1978 Matlab field research area L H
[58] Egypt (Epidemiology Study Center Field research area near Bilbeis) 0.21 1982 8 villages were selected in the Epidemiology Study Center field research area U N
[59] Gambia (Bakau) 0.51 1982 representative 55% sample of locally born children PL H
[60] Brazil (peripheral area of Belem) 0.22 1984 poor housing, low socioeconomic level L N

Inc: incidence; SocioEconomic Status (ses): low (L: study group living in poor, crowded area), probably low (PL: studies performed in developing countries), not low (NL: studies performed in developed countries) or unclear (U). NR: not reported, N: no high risk of bias, P: possible high risk of bias and H: high risk of bias in the reported incidences.

1

children were followed for the first year of life only.