Fig. 3.
The involvement of p38MAPK in C-K-mediated cell death. (A) CRT-MG cells were incubated in the absence or presence of various MAPK inhibitors for 1 h, and then they were treated with C-K or Rh2 for an additional 24 h, and cell death was measured by MTT assay. (B) The cells were treated with C-K (25 mg/L) for varying time periods, and the total cell lysates were subjected to western blot analysis for p38 MAPK, phospho-p38 MAPK and β-actin.