Table II.
Relative fold change of protein expression in OTCs with FsIL1ra compared with FCTRL
| Cytokines/growth factors | Fold increasea |
| KGFb | 5.47 ± 0.22c |
| IL-6b | 6.11 ± 0.31c |
| IL-8 | 3.47 ± 0.06c |
| IL-10 | 3.88 ± 0.15c |
| IL-16 | 3.78 ± 0.41c |
| GMCSFb | 7.74 ± 0.31c |
| CXCL1/GRO-α | 2.67 ± 0.16d |
| SDF-1 | 2.33 ± 0.07d |
| I-309 | 4.57 ± 0.20c |
| Eotaxin-2 | 6.19 ± 0.62c |
| VEGF | 0.22 ± 0.030d |
| PIGF | 0.25 ± 0.021d |
GRO-α, growth-related oncogene-α.
a
The intensities of signals were quantified by densitometry. Positive control included in the array blot was used to normalize and compare the results from different membranes. Values obtained from the control KCTRL/FCTRL OTC were arbitrarily assigned a value of 1. Values represent the mean fold increase as compared with control OTC (n = 3).
b
ChIP was performed on these genes using phospho–c-Jun antibody.
c
P < 0.01.
d
P < 0.1.