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. 2009 Apr 16;113(24):6161–6171. doi: 10.1182/blood-2008-10-187138

Table 1.

Nomenclature of bsAb constructs made by DNL

CH3-AD2-IgG module CH1-Fab-DDD2 module
22-20 CH3-AD2-IgG-e-mab CH1-DDD2-Fab-v-mab
20-22 CH3-AD2-IgG-v-mab CH1-DDD2-Fab-e-mab
20-14 CH3-AD2-IgG-v-mab CH1-DDD2-Fab-hMN-14
734-20 CH3-AD2-IgG-h734 CH1-DDD2-Fab-v-mab
20-20 CH3-AD2-IgG-v-mab CH1-DDD2-Fab-v-mab
22-22 CH3-AD2-IgG-e-mab CH1-DDD2-Fab-e-mab

Each construct is composed of 2 Fabs of the specificity indicated preceding the dash and 4 Fabs of the specificity indicated after the dash.

20 indicates anti-CD20; 22, anti-CD22; 14, anti-CEACAM5; and 734, anti-In-DTPA.