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. Author manuscript; available in PMC: 2010 Jul 29.
Published in final edited form as: Tetrahedron Lett. 2009 Jul 29;50(30):4310–4313. doi: 10.1016/j.tetlet.2009.05.031

Table 2.

Optimization of reaction conditions of sulfenylation of 1g with 1-phenylsulfanyl[1,2,4]triazole 2b.

graphic file with name nihms119708f5.jpg
entry solvent temp, °C catalyst eq. of 2b yield,a %
1 CH2Cl2 rt 4c 2.0 79
2 Toluene rt 4a 2.0 60
3 Toluene rt 4b 2.0 65
4 Toluene rt 4c 2.0 91
6 Toluene 0 4c 3.0 97
5 PhH/PhMe (3:1) −10 4c 3.0 96
a

Yield of purified product after chromatographic separation.