Table 1.

PARP-3 expression levels in various tissues of adult cynomolgous monkeys

Tissuea	Histological localizationb	Proportion of cellsc	Immunostaining intensityd
Nervous system
Cerebrum	Neuroglial cells	Majority	++
	Neurons	Some	++
Spinal cord	Neuroglial cells	Majority	++
	Neurons	Some	+
Terminal ganglia	Neurons	Some	+++
	Satellite cells	Majority	++
Peripheral nerve	Schwann cells	Majority	++
Heart	Myocardial cells	Majority	+++
Smooth muscles	Muscle cells	Some	++
Skeletal muscles	Muscle cells	All	−
Skin	Epidermal cells	Majority	+
	Sebaceous glands	Majority	++
	Apocrine sweat glands	Majority	++
	Hair follicles	Some	+
Mammary gland	Secretory and ductal cells	Majority	+
Salivary glands	Acinar cells	All	−
	Intercalated duct cells	Majority	+
	Striated duct cells	Majority	++
	Excretory duct cells	Majority	+++
Gastrointestinal tract
Stomach	Parietal cells	Majority	+
Duodenum	Absorptive epithelial cells	Majority	++
	Glandular epithelia	All	−
Colon	Goblet and columnar epithelial cells	Majority	+
Liver	Epithelial cells, small bile ducts	Majority	+
	Epithelial cells, large bile ducts	Majority	+++
	Hepatocytes	All	−
Pancreas	Acinar cells	All	−
	Centroacinar cells	Majority	++
	Ductal cells	Majority	+++
	Langherans cells	Some	++
Lung	Ciliated and Clara cells	Some	++
	Septal cells	Some	++
	Alveolar epithelial cells	Majority	+
Kidney	Podocytes	Majority	+++
	Collecting duct cells	Majority	++
	Proximal convoluted tubule cells	Majority	++
	Distal convoluted tubule cells	All	−
Spleen
White pulp (germinal center and marginal zone)	Reticular cells	Majority	++
	Lymphocytes	All	−
Red pulp	Endothelial cells of venous sinuses	Majority	+++
	Macrophages	Majority	++
Thymus	Epithelial reticular cells	Majority	++
	Lymphocytes	All	−
Endocrine glands
Adrenal gland	Zona glomerulosa	Majority	++
	Zona fasciculata	Majority	++
	Zona reticularis	Some	+
	Medulla	Majority	++C
Pituitary gland	Pars tuberalis - basophils	Majority	+++
	Pars distalis - basophils	Majority	+++
	Pars intermedia	Majority	+
Female reproductive system
Ovary	Oocytes	All	−
	Primordial follicular cells	Majority	+
	Granulosa lutein cells	Majority	+++
	Theca lutein cells	All	−
Oviduct	Epithelial cells	Majority	++
Vagina	Stratified squamous epithelium	All	−
	Deep epithelium	Some	+
Male reproductive system
Prostate	Cranial and caudal lobe cells	Majority	+
	Ductal cells	Majority	+++
Epididymis	Head and corpus epithelial cells	Majority	++
	Tail epithelial cells	Majority	+
Testis	Leydig's cells	Majority	++
	Sertoli cells	Majority	+
	Spermatocytes	All	−
Seminal vesicle	Epithelial cells	All	−
	Stromal cells	Majority	+

^aTissues that are not mentioned were not available.

^bCells that are not mentioned were not labeled.

^cIn many tissues, only a fraction of the listed cell types were labeled. Proportions of cells with the indicated staining intensity are given.

^d+: weak; ++: moderate; +++: strong; −: no staining detected. Staining was detected in the nucleus unless specified as ++C, indicating cytoplasmic staining.

PARP-3, poly(ADP-ribose) polymerase 3.