Table 3.
Known Plasmodium spp. Antigen TAP PCR Reaction Details
| Plasmodium spp. gene | Size (bp)* | Region Amplified | Yield^ |
|---|---|---|---|
| PyCSP | 1173 | Full length | + |
| PyMSP1 | 1386 | Full length | ++ |
| PyHEP17 | 665 | Full length | +++ |
| PySSP2 | 2478 | Full length | + |
| PfCSP | 1194 | Full length | ++ |
| PfMSP1-42kD | 1191 | 42kD C-terminal region | +++ |
| PfAMA1 | 1869 | Full length | +++ |
| PfEBA175-RII | 1851 | Region II | ++ |
| PfEXP1 | 489 | Full length | + |
| PfSSP2 | 1728 | Full length | +/− |
Size is for malaria antigen alone without promoter/terminator sequences.
For final product; Scale: −, +/−, +, ++, +++
Unless otherwise specified the following conditions were used: First Reaction: 94°C for 1 min, then 32 cycles of three-temperature PCR at 94°C for 30 sec, 60°C for 1 min, 68°C for 2 min, followed by a final extension time at 68°C for 10 min. Second Reaction: 94°C for 1 min, then 32 cycles of 94°C for 30 sec, 60°C for 2 min, 68°C for 3 min, followed by a final extension at 68°C for 10 min.