Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Apr 30;37(11):3475–3492. doi: 10.1093/nar/gkp244

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 8. — Regression followed by recombination of the extruded dsDNA end. Any exonucleolytic processing of the dsDNA end generated by fork regression might result in generation of a 3′ ssDNA tail rather than complete degradation (A–C). Recombination between this ssDNA and the homologous sequence in the reformed parental duplex would result in formation of a D-loop linked to two Holliday junctions (D). Cleavage of the two linked Holliday junctions by resolvases (as shown in E) or dissolution by a RecQ-type helicase in conjunction with a topoisomerase, coupled with reassembly of the replisome at the D-loop would restore a replication fork (F).