. Author manuscript; available in PMC: 2009 Jun 22.

Published in final edited form as: Bone Marrow Transplant. 2008 Aug 4;42(6):365–377. doi: 10.1038/bmt.2008.215

Table 2.

Clinical outcomes of unrelated adult marrow vs cord blood transplantation for leukemia in children

Graft	TRM (%)	Relapse (%)	LFS (%)	OS (%)
BM, allele matched at HLA-A, -B, -C, -DRB1	19	41	38	45
CB, A, B, antigen-matched, DRB1 allele matched	6	34	60	63
CB, 1-locus mismatched, high cell dose	29	31	41	45
CB, 1-locus mismatched, low cell dose	43	21	37	36
CB, 2-loci mismatched any cell dose	49	20	33	33

Abbreviations: CB = cord blood; LFS = leukemia-free survival; OS = overall survival; TRM = treatment-related mortality. Low cell dose, ≤ 3.0 × 10⁷ nucleated cells per kg; high cell dose, > 3.0 × 10⁷ nucleated cells per kg. From Eapen et al.¹²⁵