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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Clin Cancer Res. 2009 Feb 17;15(5):1747–1754. doi: 10.1158/1078-0432.CCR-08-1420

Figure 1.

Figure 1

The differences in the vascular volumes (Vp) and blood-brain barrier permeability (Ktrans) in three dose intervals at three observation times compared to the baseline values. In the high dose region (> 40 Gy), the vascular volumes increased significantly at week 6 during the course of RT and then started decreasing after the completion of RT; while in the intermediate dose interval (20−40 Gy), the vessel volume increased slowly, reached the similar maximum value 1 month after the completion of RT, and then started decreasing. The changes in the blood-brain barrier permeability were significant in the high and intermediate dose regions at week 6 during the course of RT. 10 weeks: 1 month after the completion of RT; and 32 weeks: 6 months after the completion of RT.