Table 1.
Significant results in AIDS association tests for Cox Proportional Model
| Haplogroup | pop | Endpoint | N events | N | RH | 95% CI | p |
|---|---|---|---|---|---|---|---|
| IWX | MSM | AIDS’93 | 285 | 452 | 0.65 | 0.42–1.01 | 0.0426 |
| IWX | MACS | AIDS’93 | 240 | 384 | 0.64 | 0.4–1.03 | 0.0490 |
| IWX | MSM | CD4<200 | 234 | 452 | 0.56 | 0.33–0.96 | 0.0215 |
| IWX | MACS | CD4<200 | 194 | 384 | 0.52 | 0.29–0.94 | 0.0170 |
| X | MACS | CD4<200 | 193 | 383 | 0.00 | 0-∞ | 0.0329 |
| W | MSM | AIDS’87 | 206 | 455 | 0.35 | 0.11–1.1 | 0.0316 |
| W | MACS | AIDS’87 | 179 | 387 | 0.36 | 0.11–1.12 | 0.0366 |
| W | MSM | AIDS’93 | 285 | 452 | 0.41 | 0.17–1 | 0.0225 |
| W | MACS | AIDS’93 | 240 | 384 | 0.44 | 0.18–1.08 | 0.0420 |
| W | SFCC | AIDS’93 | 45 | 68 | 0.00 | 0-∞ | 0.0369 |
| W | MSM | CD4<200 | 234 | 452 | 0.32 | 0.1–1.01 | 0.0191 |
| W | MACS | CD4<200 | 194 | 384 | 0.36 | 0.11–1.14 | 0.0402 |
| U5a | EA | CD4<200 | 339 | 615 | 1.78 | 1.11–2.85 | 0.0277 |
| U5a | MSM | CD4<200 | 236 | 453 | 2.06 | 1.17–3.63 | 0.0237 |
| U5a1-15218 | EA | AIDS’93 | 395 | 620 | 1.77 | 1.05–2.98 | 0.0493 |
| U5a1-15218 | EA | CD4<200 | 338 | 614 | 1.99 | 1.18–3.38 | 0.0197 |
| U5a1-15218 | MSM | CD4<200 | 235 | 452 | 2.04 | 1.13–3.67 | 0.0317 |
| U5b | SFCC | Death | 21 | 69 | 0.00 | 0-∞ | 0.0182 |
| U1811* | SFCC | Death | 21 | 69 | 10.07 | 1.51–67.39 | 0.0372 |
| U4-U1811* | SFCC | Death | 21 | 69 | 10.07 | 1.51–67.39 | 0.0372 |
| U4 | EA | AIDS’93 | 396 | 620 | 2.40 | 1.12–5.15 | 0.0464 |
| Uk | MSM | AIDS’87 | 206 | 456 | 0.53 | 0.29–1 | 0.0309 |
| J | EA | AIDS’87 | 277 | 628 | 1.55 | 1.08–2.23 | 0.0236 |
| J | MSM | AIDS’87 | 206 | 457 | 1.84 | 1.22–2.76 | 0.0061 |
| J | MACS | AIDS’87 | 179 | 388 | 1.69 | 1.08–2.66 | 0.0302 |
| J | EA | Death | 239 | 627 | 1.53 | 1.03–2.26 | 0.0428 |
| J1 | EA | AIDS’87 | 277 | 627 | 1.57 | 1.03–2.38 | 0.0463 |
| J1 | MSM | AIDS’87 | 206 | 456 | 1.80 | 1.12–2.87 | 0.0228 |
| J1 | MACS | AIDS’87 | 179 | 388 | 1.91 | 1.13–3.25 | 0.0263 |
| J1c | EA | AIDS’87 | 277 | 626 | 1.67 | 1.07–2.61 | 0.0338 |
| J1c | MSM | AIDS’87 | 206 | 456 | 1.94 | 1.18–3.17 | 0.0159 |
| J1c | MACS | AIDS’87 | 179 | 388 | 2.25 | 1.27–3.98 | 0.0116 |
| J1c | MSM | AIDS’93 | 287 | 453 | 1.64 | 1.05–2.55 | 0.0408 |
| J1c | MACS | AIDS’93 | 241 | 385 | 1.82 | 1.08–3.09 | 0.0383 |
| J1c | EA | Death | 239 | 625 | 1.72 | 1.07–2.78 | 0.0381 |
| J1c-14798* | EA | AIDS’87 | 277 | 626 | 1.80 | 1.12–2.91 | 0.0247 |
| J1c-14798* | MSM | AIDS’87 | 206 | 456 | 2.24 | 1.3–3.84 | 0.0082 |
| J1c-14798* | MACS | AIDS’87 | 179 | 388 | 2.01 | 1.09–3.7 | 0.0403 |
| J1c-14798* | SFCC | AIDS’87 | 27 | 68 | 6.23 | 1.33–29.23 | 0.0351 |
| J1c-14798* | EA | Death | 239 | 625 | 2.03 | 1.24–3.33 | 0.0101 |
| J1c-14798* | MSM | Death | 175 | 455 | 2.27 | 1.27–4.05 | 0.0123 |
| J1c-14798* | SFCC | Death | 21 | 68 | 9.13 | 1.68–49.67 | 0.0177 |
| J2 | SFCC | AIDS’87 | 27 | 68 | 63.69 | 3.61–1124.28 | 0.0194 |
| J2 | SFCC | AIDS’93 | 46 | 68 | 44.26 | 3.71–528.15 | 0.0236 |
| J2 | SFCC | CD4<200 | 41 | 68 | 23.13 | 2.33–229.65 | 0.0441 |
| T | HE | AIDS’87 | 68 | 159 | 0.30 | 0.11–0.86 | 0.0125 |
| H1 | HE | AIDS’87 | 68 | 159 | 2.38 | 1.11–5.09 | 0.0386 |
| H1 | MHCS | AIDS’87 | 68 | 159 | 2.38 | 1.11–5.09 | 0.0386 |
| H1 | SFCC | AIDS’93 | 46 | 68 | 0.00 | 0.0317 | |
| H1 | EA | Death | 240 | 629 | 1.50 | 1.04–2.16 | 0.0403 |
| H3 | HE | AIDS’87 | 68 | 159 | 0.12 | 0.02–0.94 | 0.0060 |
| H3 | HE | AIDS’93 | 104 | 156 | 0.21 | 0.06–0.72 | 0.0025 |
| H3 | HE | Death | 63 | 159 | 0.00 | 0-∞ | 0.0004 |
| H5 | EA | Death | 239 | 626 | 0.39 | 0.15–1.07 | 0.0326 |
| H5 | MSM | Death | 175 | 456 | 0.30 | 0.07–1.21 | 0.0381 |
| H6 | HE | AIDS’93 | 104 | 155 | 0.07 | 0.01–0.66 | 0.0040 |
| V | HE | Death | 62 | 157 | 7.76 | 1.61–37.44 | 0.0381 |
| HV* | SFCC | AIDS’87 | 27 | 68 | 28.37 | 2.1–383.55 | 0.0418 |