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. Author manuscript; available in PMC: 2010 Jun 9.
Published in final edited form as: Biochemistry. 2009 Jun 9;48(22):4816–4827. doi: 10.1021/bi9002265

Fig. 4.

Fig. 4

α-Gal A structures. (A) Superposition of apo α-Gal A (beige), galactose-bound α-Gal A (silver), and DGJ-bound α-Gal A (purple). (B) Active site region of DGJ-bound α-Gal A. Fo-Fc difference density immediately following original molecular replacement solution is contoured at 2.5 •. (C) Active site region of galactose-bound α-Gal A. Fo-Fc difference density immediately following original molecular replacement solution at 3 •. (D) Schematic diagram of hydrogen bonding interactions involved in stabilizing galactose in the active site of DGJ.