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. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Gynecol Oncol. 2007 Oct 18;108(1):3–9. doi: 10.1016/j.ygyno.2007.09.007

Table 3.

Mean number of HER-2 and CEP17 copies per cell, copy number ratios and proportion of cells aneusomic for chromosome 17 in uterine serous papillary carcinoma (USPC) versus all other histologic subtypes of endometrial cancer.

Parameter Mean copy number (Standard Deviation) Pr > Chi- Square*
UPSC (n=28) Other EC (n=141)
HER-2 3.8 (2.45) 3.64 (6.78) <0.001
CEP17 2.13 (0.56) 1.90 (0.51) 0.04
HER-2/CEP17 1.86 (1.33) 1.89 (3.11) 0.06
Mean percentage of cells
Monosomic + 33 39 0.14
Polysomic ++ 30 20 0.03
Aneusomic +++ 63 59 0.18
*

Kruskal-Wallis Test;

+

percentage of cells with reduction of chromosome 17 to one copy;

++

proportion of cells with gain of chromosome 17 to three or more than three copies per cell;

+++

Monosomic+Polysomic.