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. 2006 Dec;1(4):327–348. doi: 10.2147/ciia.2006.1.4.327

Table 1.

Comparison of chronological aging and photoaging

Ageing types Identification characteristics
Epidermis Dermis Clinical
Chronological aging Thinner than normal with lower cell growth, minor abnormalities in keratinocyte regularity
Normal stratum corneum
There is loss of rete pegs here as well
Elastin fibers appear irregular in their arrangement, whereas collagen fibers begin to lower in number and thickness  Skin is smooth, unblemished, but shows saggy appearance
Photoaging Thick skin, with acanthosis followed by atrophy of the cells
High basal keratinocyte irregularity Stratum corneum appears compact
There is loss of rete pegs here as well
Excessive production of elastin fibers in an improper orientation, collagen fibres appear to thicken and then wear out soon
Appearance of grenzzone
Smooth, leathery, reddened appearance with initially light wrinkles, which later deepen, thus showing loss of collagen fibers