Table 3.
Studies of persistence with weekly compared with daily bisphosphonate regimens
| Study | Dose regimens (n) | Days to treatment discontinuation | Days of treatment duration |
|---|---|---|---|
| IHCIS database (1997–2002) (Cramer et al 2005) | Daily alendronate or risedronate (2010) | 185 | 134 |
| Weekly alendronate (731) | 227 | 269 | |
| IMS Mediplus(Bartl et al 2006) | Daily alendronate (144) | 153 | – |
| Weekly alendronate (144) | 212 | – | |
| NDCHealth retrospective database (Ettinger et al 2004; Sunyecz et al 2004) | Daily alendronate or | – | 198 |
| risedronate (33767) | |||
| Weekly alendronate or risedronate (177552) | – | 238 |