. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Anesthesiology. 2009 Mar;110(3):582–590. doi: 10.1097/ALN.0b013e318197941e

Table 2.

Inhaled anesthetic effects on Na_v1.4 current decay.

	τ_in, ms
	Control	Anesthetic	Concentration, mM	n
Isoflurane	0.54 ± 0.08	0.47 ± 0.08^*	0.46 ± 0.05	8
	0.52 ± 0.09	0.43 ± 0.08^*	0.85 ± 0.04	6
Halothane	0.51 ± 0.07	0.42 ± 0.04^*	0.43 ± 0.03	5
	0.55 ± 0.07	0.39 ± 0.06^†	0.81 ± 0.04	5
Desflurane	0.55 ± 0.10	0.40 ± 0.05^*^‡	0.80 ± 0.06	7
	0.54 ± 0.09	0.34 ± 0.08^†^‡^§	1.65 ± 0.14	5

Values are mean ± SEM.

P < 0.01,

^†

P < 0.001 vs. respective control by unpaired t test.

^‡

P < 0.05 vs. isoflurane,

^§

P < 0.05 vs. halothane by one-way analysis of variance with Newman-Keuls post hoc test. τ_in = time constant of current decay calculated for a prepulse potential of −120 mV.