Skip to main content
. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Am J Obstet Gynecol. 2007 May;196(5):433–444. doi: 10.1016/j.ajog.2006.11.041

Table III.

Proposed “Definite” causes of death

Maternal death
 unintentional injuries
  Toxic (including teratogenic) injury
  Physical injury
 Homicide
 Suicide
 Complications of medical and surgical care
  Therapeutic drug or radiation exposure during pregnancy
  Intra-gestational uterine surgery
 Diseases that cause maternal death during pregnancy
  Neoplasia
  Cardiovascular diseases
  Hematological diseases
  Infectious diseases
Birth injuries
 Uterine rupture
 Dystocia or malpresentation
  Attempted instrumental vaginal delivery
  Without attempted instrumental vaginal delivery
Placental lesions (excluding infection)
 Umbilical cord lesions with clinical and/or histologic evidence of umbilical cord vessel obstruction
  Umbilical cord prolapse
  True knots with evidence of circulatory compromise
  Strangulation due to long cord
  Furcate insertion
  Velamentous insertion
  Neoplasms of the umbilical cord
 Lesions involving the placental parenchyma
  Abruptio placenta
  Intraparenchymal thrombi/fibrin deposition involving the entire   placental
  parenchyma
  Infarction of the entire placental parenchyma
  Neoplasms or developmental lesions involving the entire placental parenchyma
   Mesenchymal dysplasia
   A-V malformations etc.
Hydrops fetalis, marked, immune or non-immune Complications multiple gestation
 Twin-twin transfusion syndrome (Advanced stage)
 TRAP (twin reversed arterial perfusion) sequence
 Strangulation due to umbilical cord entanglement (Monoamnionic-monochorionic gestations)
Lethal congenital developmental conditions
 Fetal aneuploidy
  Chromosome 19, mosaic trisomy 19
  Tetraploidy 92XXXX,92XXYY
  Triploidy 69XXX,69XXY
 Bony dysplasias with thoracic constriction and evidence of hemodynamic compromise.
  Achondrogenesis
  Asphyxiating thoracic dysplasia
  Camptomelia, short gut, polycystic kidney/liver, polysplenia
  Chondrodysplasia sequences
  Hypochondrogenesis
  Osteogenesis imperfecta congenita IIa
  Short rib-polydactyly syndromes
  Spondylohypoplasia, arthrogryposis, popliteal pterygium
 Fetal akinesia sequence
 Lethal multiple pterygium syndrome
Infections
 Chronic fetal/placental infection, fulminant
  Syphilis
  Rubella
  Toxoplasmosis
  Cytomegalovirus
 Acute fetal/placental infection, fulminant
  Herpes simplex
  Varicella
  Cytomegalovirus