Table 2.
Intraoperative and postoperative data
| Group 1 PPV | Group 2 Avastin + PPV | P value (w) | P value (chi) | |
|---|---|---|---|---|
| Bleeding frequency (times/surgery) | ||||
| mean (SD)/(range) | 6.8 (1.5)/(4–9) | 1.9 (1.1)/(0–4) | <0.0001 | |
| Diathermy frequency (times/surgery) | ||||
| mean (SD)/(range) | 4.6 (1.2)/(2–6) | 0.27 (0.46)/(0–1) | <0.0001 | |
| Surgical time (min.) | ||||
| mean (SD)/(range) | 93.3 (11.6)/(70–110) | 61.6 (14.5)/(40–90) | <0.0001 | |
| PFCL use, n (%) | 8 (53.3) | 3 (20) | ||
| Relaxing retinotomy, n (%) | 4 (26.6) | 2 (13.3) | ||
| Endotamponade, n (%) | ||||
| 20% SF6 | 6 (40) | 9 (60) | ||
| Air | 0 | 3 (20) | ||
| Silicone oil | 9 (60 ) | 3 (20) | ||
| VA pre surgery | ||||
| mean (± lines)/(range) | 0.016 (6.2)/(HM −0.1) | 0.01(7.3)/(HM −0.1) | P2 < 0.001 | |
| VA post surgery (final) | P = 0.52 | |||
| mean (± lines)/(range) | 0.12 (6.7)/(HM −0.5) | 0.18 (6.8)/(HM −0.6) | P1 = 0.003 | |
| VA change, n (%) | ||||
| Better | 12 (80) | 13 (86.6) | ||
| Same | 2 (13.3) | 2 (13.3) | ||
| Worse | 1 (6.7) | 0 | ||
| Primary attachment, n (%) | 13 (86.6) | 14 (90.3) | 1 | |
| Subsequent surgeries, n (%) | ||||
| Cataract + oil removal | 7 (46.7) | 3 (20) | ||
| Re-PPV | 2 (13.3) | 1 (6.7) | ||
| Postoperative complications | ||||
| Cataract, progressive | 7 (46.7) | 4 (26.6) | ||
| Cataract, gas-induced | 2 (13.3) | 3 (20) | ||
| Postoperative bleeding | 4 (26.6) | 0 | ||
| Rubeosis | 1 (6.7) | 0 | ||
| Optic pallor | 0 | 1 (6.7) | ||
| Corneal erosions | 5 (33.3) | 2 (13.3) | ||
Abbreviations: PPV, pars plana vitrectomy; VA, best corrected visual acuity; ww, Wilcoxon two-sample test; chi, chi square test; P1, preoperative versus final VA in group1; P2, preoperative versus final VA in group 2; P, p value, visual change between the two groups; SD, standard deviation; min, minutes; PFCL, perfluorocarbon liquid.