Figure 3.

Kinetics of dephosphorylation in phosphorylated 334Ser and 338Ser in control and P23H rats. Four-week-old control and P23H rats were exposed to regular room light (650 lux) for 6 h and then were maintained under dark condition. Rho phosphorylation level was evaluated at three different time points (0, 1, 2, 3, 4, 6, 12, 24, 48, 72, and 96 h, n = 3 per group), with immunofluorescence labeling by anti-P-Rho antibodies. Vertical length of photoreceptor outer segment layers and that of fluorescence labeling was measured at temporal points 1.0 mm apart from optic disc from 6 different points from 3 different eyeballs and their ratios were plotted.

Notes: Data are expressed as the mean ± SD; Closed circle (SD rat); closed square (P23H rat).