Table 2.

Eighteen Patients with Endometrial Cancer had MMR Gene Mutations in Germ Cells

No.	Age	Type	Grade	Stage	Group	Mutation Type	Report	Double Cancer
K007	42	EM/CL	G2	3c	AB	hMLH1 ex3 codon100 Nonsense	+	CC(42yo)
K009	42	EM	G1	1b	A	hMSH6 ex5 codon1085 Frameshift	+	−
K017	34	EM	G2	1b	A	hMSH2 ex10 codon554 Missense	−	−
K023	56	EM	G1	1a	A	hMSH6 ex4 codon795 Frameshift	−	−
K030	52	EM	G2	3a	A	hMSH6 ex4 codon546 Frameshift	−	−
K031	54	EM	G2	1a	A	hMSH2 ex11 codon582 Frameshift	−	−
T004	56	EM	G1	3a	A HNPCC	hMSH2 ex13 codon680 Nonsense	+	−
T011	65	AS	G1	3a	B	hMSH6 ex6 codon1163 Missense	−	BC(65yo)
T016	41	EM	G1	1b	AB HNPCC	hMSH2 ex5 codon288 Nonsense	+	CC(38,50yo)
J001	48	EM	G1	1b	AB HNPCC	hMLH1 ex16 codon618 Deletion	+	CC(44yo)
J015	53	EM	G1	1a	B	hMSH6 ex4 codon744 Frameshift	−	OvC(53yo)
J021	55	EM	G1	1b	A	hMSH6 ex4 codon482 Nonsense	−	−
G001	52	EM	G1	3c	AB HNPCC	hMLH1 ex13 Splicing	+	CC(48,50yo)
G030	57	EM	G2	1b	B	hMSH6 ex10 codon1355 Frameshift	−	BC(39yo)
G032	62	EM	G3	1a	A	hMSH6 ex4 codon487 Frameshift	−	−
G036	50	EM	G1	1a	A	hMSH6 ex4 codon742 Missense	−	−
F001	37	EM	G1	1a	B	hMLH1 ex12 codon384 Missense	−	CC(36yo)
F002	46	EM	G1	1b	AB	hMLH1 ex16 codon618 Deletion	+	CC(46yo)

CC: Colorectal Cancer, BC: Breast Cancer, OvC: Ovarian Cancer.