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Intracellular cGMP produced in oocytes in response to SNP. Oocytes were tested in conditions comparable to those used for electrophysiological analyses, being assayed after 4 minutes of treatment with various concentrations of SNP in K+ recording saline. The amount of cGMP per oocyte was measured by enzyme immunoassay. Each point represents the mean of duplicate or triplicate measurements from four different experiments (separate batches of oocytes). Values shown are mean ± SEM.
