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. 2003 Oct 15;3:12. doi: 10.1186/1472-6793-3-12

Figure 4.

Figure 4

Inhibition of soluble guanylate cyclase prevents the AQP1 conductance response to SNP. Wild type AQP1-expressing and control oocytes were incubated three hours in ND96 saline with or without an inhibitor of soluble guanylate cyclase (1H-[1,2,4]oxadiazolo [4,3-a]quinoxalin-1-one, ODQ, 10 μM) prior to electrophysiological analysis of the response to SNP (doses indicated in mM on horizontal axis). Data are mean ± SEM; n = 3 or 4 oocytes per group. An asterisk (*) indicates values that are significantly different (p < 0.04) from control; the pound sign (#) indicates values that are significantly different (p < 0.04) from wild type AQP1 (unpaired two-tailed Student's t test).