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. 2009 Mar;10(1):18–25. doi: 10.2174/138920209787581307

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©2009 Bentham Science Publishers Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. (3) — Surface representation of the AR coactivator groove. Representation of the AR AF-2 surface highlighting the L-shaped cleft and key residues important in coactivator binding. +1, +4 and +5 refer to the regions in which the 1^st, 4^th and 5^th amino acids of LxxLL and FxxLF-like motifs lie following binding. Image created using RasMol V2.6 using co-ordinates from [30].