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. 2009 Apr 28;58(7):1672–1681. doi: 10.2337/db08-0183

FIG. 3.

FIG. 3.

High glucose induces Col8a1. A: Increased d-glucose concentrations (from 100 to 450 mg/dl) raised the Col8a1 mRNA in tubular epithelial (MCT) and mesangial (MMC) cells but not in glomerular endothelial cells (GER) in Northern blots. B: High glucose increased the Col8a1 mRNA expression in MMCs after 6 h. C: mRNA of murine corneal endothelial cell (mCEC) represent a positive control. D: Representative real-time PCR analyses on glucose-treated MMCs. Increased d-mannitose concentrations had no effect on the Col8a1 expression.