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Porcine insulin blood levels 10 weeks after transplantation of E42 pancreas into immunosuppressed C57BL/6 mice. Recipients were treated with different combinations of costimulatory blockade agents (anti-LFA1, anti-CD48, and CTLA4-Ig) and FTY720, with or without T-cell debulking. Data are presented as means ± SE. *P ≤ 0.05.
