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. 2009 Apr 29;58(7):1604–1615. doi: 10.2337/db09-0058

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© 2009 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — A: Typical islets from wild-type (WT) rats, HIP rats, HIP rats treated with sitagliptin (HIP+SIT), and HIP rats treated with sitagliptin and metformin (HIP+SIT+MET) stained for insulin (pink) and hematoxylin (blue). β-Cell area (B) and mean β-cell mass (C) after 12-week treatment with 60% high-fat diet in wild-type rats (n = 7), HIP rats (n = 8), HIP rats treated with sitagliptin (HIP+SIT; n = 8), HIP rats treated with metformin (HIP+MET; n = 9), and HIP rats treated with combination therapy (HIP+SIT+MET; n = 8). Data are the means ± SE. (A high-quality digital representation of this figure is available in the online issue.)