Table 5.
Quantification of human plasma proteins binding to lipid-polymer hybrid NPs with different surface functional groups.
| Human plasma proteins | COOH | CH3O | NH2 |
|---|---|---|---|
| Amount of protein bound | |||
| Factor H | 0.61 | 1 | 1.09 |
| Complement component C6 precursor | 1.10 | 1 | 1.17 |
| Complement C1r subcomponent precursor | 1.04 | 1 | 1.07 |
| Fibrinogen α chain | 0.83 | 1 | 1.18 |
| Fibrinogen β chain | 1.18 | 1 | 1.06 |
| Fibrinogen γ chain | 1.16 | 1 | 0.96 |
| Apolipoprotein IV | 1.31 | 1 | 1.27 |
| Apolipoprotein E | 1.22 | 1 | 1.05 |
| Apolipoprotein AI | 0.89 | 1 | 1.32 |
| Serum amyloid A-4 protein precursor | 1.06 | 1 | 1.03 |
| Apolipoprotein C-III | - | 1 | 1.03 |