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. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Exp Hematol. 2008 Mar;36(3):283–292. doi: 10.1016/j.exphem.2007.11.009

Figure 2. MGMTP140K expression in transplanted mice treated with vehicle or submyeloablative therapy.

Figure 2

(A) Western analysis of BM from mice transplanted with MD9-P140K-transduced Linneg BM cells and selected in vivo. Data from experiment #2 are shown. (B) MGMT specific activity in pooled progenitor colonies derived from BM of control, vehicle- and drug-treated mice. Forty progenitor colonies were randomly plucked at 12-14 days after plating and analyzed for MGMT repair activity. These data are representative of individual mice from experiments 1 and 2. Specific activity = fmol O6 methylguanine removed per mg total protein.