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. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Exp Hematol. 2008 Mar;36(3):283–292. doi: 10.1016/j.exphem.2007.11.009

Table 1.

Overview of primary transplantation experiments.

Experiment 6BG/BCNU dose Vehicle-treated mice 6BG/BCNU-treated mice
survival MGMTP140K expression survival MGMTP140K expression
1 submyeloablativea 3/4 0/4 6/6 3/6
2 submyeloablative 4/4 1/4 5/6 3/5
3 myeloablativeb 4/4 0/4 2/6 2/2
4 myeloablative 3/4 0/4 1/6 1/1
a

20 mg/kg 6BG followed one hour later by 5 mg/kg BCNU administered at 4 weeks and 6 weeks post-transplantation.

b

30 mg/kg 6BG followed one hour later by 10 mg/kg BNCU and 15 mg/kg 6BG 7 hours after initial 6BG bolus administered at 4 weeks and 6 weeks post-transplantation.