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. Author manuscript; available in PMC: 2010 May 25.
Published in final edited form as: Physiol Behav. 2009 Mar 9;97(2):229–238. doi: 10.1016/j.physbeh.2009.02.035

Figure 3. Associative learning increases neurogenesis in the male and female hippocampus.

Figure 3

a. The density of adult generated cells (BrdU-labeled cells) in the dentate gyrus of the hippocampus is enhanced in rats trained with trace eyeblink conditioning, in comparison to untrained animals. The percent increase is greater in trained females (34%) than in trained males (17%). The density of new cells in untrained females is lower than that in untrained males (significant differences are noted with an *) [47].

b. A representative picture of the dentate gyrus is shown (magnified 20×). In the smaller panel (magnified 1000×), the new cells in the dentate gyrus of the adult hippocampus are stained in brown (BrdU-labeled cells). The hippocampal slice was counterstained with cresyl violet (cells shown in purple).