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. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Biochim Biophys Acta. 2007 Dec 3;1779(1):17–27. doi: 10.1016/j.bbagrm.2007.11.005

Figure 3.

Figure 3

Nucleotide sequence of the 5′-flanking region of EPHX2 from −400 nts upstream to 20 nts downstream of the putative transcriptional start site. The sequence corresponds to nts 5,722,553 to 5,722,972 of human chromosome 8 (GenBank accession no. NT_023666). The putative transcriptional start site C is marked by +1 and indicated by a bold arrow. Numbers to the left and right indicate nucleotides upstream (−) and downstream (+) of the putative transcriptional start site. Putative transcription factor binding sites (Sp1, c-Rel/NFκB, AP-1, and c-Myc/Max1) are indicated below the sequence. The 5′ ends of the nested deletions (−272 to −3) used in the promoter analysis (see Fig. 4) are indicated by arrows above the sequence. The underlined text indicates the oligonucleotides (Oligos 1 to 4) used for EMSA in Fig. 7A. The GG to TT mutation site of the −374/+28TT and −63/+28TT constructs is boxed and indicated by bold.