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(A) Enzymatic clearance of reactive oxygen species. Superoxide anions undergo dismutation by superoxide dismutase (SOD) leading to the generation of hydrogen peroxide. This in turn is processed by catalase and glutathione peroxidase (GPx). (B) Reduced glutathione (GSH) is regenerated from its oxidized form (GSSG), using NADPH, by glutathione reductase (GRx).
