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. Author manuscript; available in PMC: 2009 Jun 22.
Published in final edited form as: Neurobiol Dis. 2007 May 5;27(2):207–219. doi: 10.1016/j.nbd.2007.04.009

Figure 2. General appearance of SMNΔ7 SMA mice.

Figure 2

Apart from their smaller sizes and inability to right themselves, SMNΔ7 SMA mice (SMN2+/+;SMNΔ7+/+;mSmn−/−; asterisk) at PND04 (A) and PND07 (B) are similar in appearance to their carrier (SMN2+/+;SMNΔ7+/+;mSmn+/−; closed arrow) and normal (SMN2+/+;SMNΔ7+/+;mSmn+/+; open arrowhead) littermates. On PND11 (C) and PND14 (D), SMNΔ7 SMA mice appear small and emaciated presumably the result of neurogenic muscle atrophy.