Table 2.
entry | alcohol | aryl bromide | product | yield(b) |
---|---|---|---|---|
1 | 76% | |||
2 | 65% | |||
3 | 70% | |||
4 | 40% | |||
5 | 36% | |||
6 | 32% | |||
7 | 19% | |||
8 | 80% | |||
9 | 60% | |||
10 | 81% | |||
11 | 70% | |||
12 | 60% | |||
13 | No Reaction |
Conditions: 1.0 equiv alcohol, 2.0 equiv ArBr, 2.0 equiv NaOtBu, 1 mol % Pd2(dba)3, 2 mol % dpe-phos, THF (0.13-0.25 M), 65 °C.
Yields represent average isolated yields for two or more experiments.